Incidence of Colorectal Cancer and Adenomatous Polyps After a Two-Step Screening in Isfahan Province, Iran in 2018

• Published in: Journal of gastrointestinal cancer 2020-09, Vol.51 (3), p.850-854
• Main Authors: Soodejani, Moslem Taheri, Mirzaei, Hossein, Manesh, Marzieh Mahmoodi, Tabatabaei, Seyyed Mohammad, Ghaderi, Azimeh
• Format: Article
• Language: English
• Subjects: Adenomatous Polyps - diagnosis; Adenomatous Polyps - epidemiology; Aged; Cancer Research; Colonoscopy - statistics & numerical data; Colorectal Neoplasms - diagnosis; Colorectal Neoplasms - epidemiology; Colorectal Neoplasms - prevention & control; Early Detection of Cancer - methods; Early Detection of Cancer - statistics & numerical data; Female; Gastroenterology; Humans; Incidence; Internal Medicine; Iran - epidemiology; Male; Mass Screening - methods; Mass Screening - statistics & numerical data; Medicine; Medicine & Public Health; Middle Aged; Occult Blood; Oncology; Original Research; Patient Acceptance of Health Care - statistics & numerical data; Radiotherapy; Risk Factors; Sex Factors
• ISSN: 1941-6628; 1941-6636
• DOI: 10.1007/s12029-019-00313-x

Purpose The aim of this study was to estimate the incidence of colorectal cancers in Iran. The results of this study are based on a screening program that is being implemented in Isfahan province. Material and Methods In this study, about 137,000 people were screened for colorectal cancer and adenomatous polyps in 2 steps during the year 2018. Results Based on the findings of this study, the incidence of adenomatous polyps was reported to be 389 (95% CI, 365–422) per 100,000 population. The incidence of adenomatous polyps was reported to be 483 (95% CI, 446–520) and 316 (95% CI, 286–346) in men and women, respectively ( p < 0.001). Also, the incidence of colorectal cancer was reported to be 33 (95% CI, 23–42) per 100,000 population. The incidence of colorectal cancer in men and women was reported to be 41 (95% CI, 30–51) and 26 (95% CI, 17–34), respectively, indicating a statistically non-significant difference ( p = 0.29). Conclusion Based on the result of this study, despite a low participation rate of the target population in the screening program, the incidence of adenomatous polyps and colorectal cancer is relatively high in the average-risk population.