Polyethylene glycol in water: A simple, efficient and green protocol for the synthesis of quinoxalines

. A variety of biologically important quinoxaline derivatives has been efficiently synthesized in excellent yields under extremely mild conditions using PEG-600 and water. This inexpensive, non-toxic, eco-friendly and readily available system efficiently condensed several aromatic as well as aliphat...

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Bibliographic Details
Published in:Journal of chemical sciences (Bangalore, India) India), 2011-07, Vol.123 (4), p.477-483
Main Authors: CHAVAN, HEMANT V, ADSUL, LAXMAN K, BANDGAR, BABASAHEB P
Format: Article
Language:English
Subjects:
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
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Summary:. A variety of biologically important quinoxaline derivatives has been efficiently synthesized in excellent yields under extremely mild conditions using PEG-600 and water. This inexpensive, non-toxic, eco-friendly and readily available system efficiently condensed several aromatic as well as aliphatic 1,2-diketones with aromatic and aliphatic 1,2-diamines to afford the products in excellent yield. Polyethylene glycol (PEG) can be recovered and recycled. Graphical Abstract Biologically important quinoxaline derivatives have been efficiently synthesized in excellent yields under extremely mild conditions using PEG-600 and water.
ISSN:0974-3626
0973-7103
DOI:10.1007/s12039-011-0081-8