A revision on cryoglobulinaemia associated to neoplastic diseases

Cryoglobulinaemia is an infrequent process and has been classified in types I, II and III. Type I corresponds to monoclonal cryoglobulinaemia; types II and III are comprised in the group of mixed cryoglobulinaemias (MC). In MC type II, cryoglobulinaemias are made up of a monoclonal rheumatoid factor...

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Bibliographic Details
Published in:Clinical & translational oncology 2007-04, Vol.9 (4), p.229-236
Main Authors: Molina-Garrido, M J, Guillén-Ponce, C
Format: Article
Language:English
Subjects:
Adrenal Cortex Hormones - administration & dosage
Adrenal Cortex Hormones - therapeutic use
Aged
Antibodies, Monoclonal - administration & dosage
Antibodies, Monoclonal - therapeutic use
Antibodies, Monoclonal, Murine-Derived
Cryoglobulinemia - complications
Cryoglobulinemia - diagnosis
Cryoglobulinemia - etiology
Cryoglobulinemia - therapy
Cyclophosphamide - administration & dosage
Cyclophosphamide - therapeutic use
Diagnosis, Differential
Female
Follow-Up Studies
Hepatitis C, Chronic - complications
Humans
Immunologic Factors - administration & dosage
Immunologic Factors - therapeutic use
Immunosuppressive Agents - administration & dosage
Immunosuppressive Agents - therapeutic use
Leukemia - etiology
Lymphoma - etiology
Male
Neoplasms - etiology
Plasmapheresis
Prognosis
Randomized Controlled Trials as Topic
Rituximab
Time Factors
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Description
Summary:Cryoglobulinaemia is an infrequent process and has been classified in types I, II and III. Type I corresponds to monoclonal cryoglobulinaemia; types II and III are comprised in the group of mixed cryoglobulinaemias (MC). In MC type II, cryoglobulinaemias are made up of a monoclonal rheumatoid factor vs. a polyclonal IgG. In MC type III all compounds are polyclonal. Monoclonal cryoglobulinaemias are usually associated to malignant haematological processes, while MC are associated to systemic diseases and infection. More research is needed on the natural history, causes, treatment and evolution of cryoglobulinaemia. This revision analyses a more recent knowledge on this entity, as well as its association to neoplastic diseases.
ISSN:1699-048X
1699-3055
DOI:10.1007/s12094-007-0044-1