Effect of long-term Helicobacter pylori infection on growth of children: a cohort study

Background The effects of Helicobacter pylori ( H. pylori ) infection on growth are a controversial issue. We investigated the effects of long-term H. pylori infection on height and weight in children. Methods A total of 200 children of 7-18 years old suffering from dyspeptic complaints were classif...

Full description

Saved in:
Bibliographic Details
Published in:World journal of pediatrics : WJP 2016-05, Vol.12 (2), p.196-201
Main Authors: Kocaoglu, Celebi, Ozel, Ahmet, Cayci, Mustafa, Solak, Ece Selma
Format: Article
Language:English
Subjects:
Critical Care Medicine
Imaging
Intensive
Maternal and Child Health
Medicine
Medicine & Public Health
Original Article
Pediatric Surgery
Pediatrics
Radiology
Surgery
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background The effects of Helicobacter pylori ( H. pylori ) infection on growth are a controversial issue. We investigated the effects of long-term H. pylori infection on height and weight in children. Methods A total of 200 children of 7-18 years old suffering from dyspeptic complaints were classified into two groups: H. pylori positive and negative groups, respectively. Whether the infection was impoved was followed up while performing urea breath test, and according to exposure time to the infection, the children were further divided into group 1 (≤1.5 months), group 2 (>1.5-≤6 months) and group 3 (>6 months). Antropometric measurements were obtained and repeated every six months. Results Mean growth velocity scores in the H. pylori positive and negative groups were 0.49±3.85 [95% confidence interval (CI): -0.21-1.18] and 1.98±4.42 (95% CI: 1-2.96), respectively. The difference between both groups was statistically significant ( P =0.012). Mean growth velocity scores in groups 1, 2 and 3 were 0.96±3.84, 0.16±4.51 and -0.85±3.09, respectively. Mean growth velocity scores of group 3 were significantly lower than those of groups 0 and 1 ( P =0.005 and P =0.041). The mean weight scores in group 3 were similar to those in group 2, but the scores in group 3 were significantly lower than those in group 1 (-1.75±1.05, -1.21±1.37 and -0.88±1.49, respectively). Conclusion As the duration of exposure is prolonged in children with H. pylori infection, the negative effect of the infection on both height and weight is evident.
ISSN:1708-8569
1867-0687
DOI:10.1007/s12519-015-0021-7