Cold-loaded pain sensation test and current perception threshold for evaluating diabetic neuropathy

Objective We previously designed and reported a simple new method (the cold-loaded pain sensation test) for quantitative evaluation of the function of small nerve fibers. In the study reported here, we investigated the clinical usefulness of this test to evaluate diabetic neuropathy by comparison wi...

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Bibliographic Details
Published in:Diabetology international 2013-03, Vol.4 (1), p.34-39
Main Authors: Ohta, Akio, Kato, Hiroyuki, Nakamura, Yuta, Tenjin, Ayumi, Sakai, Kensuke, Tukiyama, Hidekazu, Terashima, Yuko, Nagai, Yoshio, Tanaka, Yasushi
Format: Article
Language:English
Subjects:
Diabetes
Endocrinology
Medicine
Medicine & Public Health
Metabolic Diseases
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Summary:Objective We previously designed and reported a simple new method (the cold-loaded pain sensation test) for quantitative evaluation of the function of small nerve fibers. In the study reported here, we investigated the clinical usefulness of this test to evaluate diabetic neuropathy by comparison with a device for quantitative measurement of the neuroselective current perception threshold (CPT). Patients and methods We evaluated 68 diabetic patients without cerebrovascular disease. After cooling the test site, the recovery time (RT) required for pain sensation to return to an equivalent level to that on the noncooled side was evaluated. The rapid screening mode was employed to measure CPT. Results RT measured at the great toe (77.8 ± 43.2 s) was significantly longer than that measured at the medial malleolus (53.8 ± 30.0 s) ( p  
ISSN:2190-1678
2190-1686
DOI:10.1007/s13340-012-0090-y