An efficient synthesis of new khellactone-type compounds using potassium hydroxide as catalyst via one-pot, three-component reaction

In the present work, three-component synthesis for novel khellactone-type compounds via the reaction of Meldrum’s acid, aryl aldehydes and 5,7-dihydroxy benzopyrone derivatives was described. In this reaction 10-aryl substituted-9,10-dihydropyrano[2,3-h]benzopyrone-8-ones as new khellactone analogou...

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Published in:Journal of the Iranian Chemical Society 2014-06, Vol.11 (3), p.631-637
Main Authors: Karami, B., Eskandari, K., Khodabakhshi, S.
Format: Article
Language:English
Subjects:
Analytical Chemistry
Biochemistry
Chemistry
Chemistry and Materials Science
Inorganic Chemistry
Organic Chemistry
Original Paper
Physical Chemistry
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description In the present work, three-component synthesis for novel khellactone-type compounds via the reaction of Meldrum’s acid, aryl aldehydes and 5,7-dihydroxy benzopyrone derivatives was described. In this reaction 10-aryl substituted-9,10-dihydropyrano[2,3-h]benzopyrone-8-ones as new khellactone analogous in the presence of catalytic amount of potassium hydroxide as cheap and green basic catalyst were obtained in good to excellent yields under refluxing methanol.
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subjects Analytical Chemistry
Biochemistry
Chemistry
Chemistry and Materials Science
Inorganic Chemistry
Organic Chemistry
Original Paper
Physical Chemistry
title An efficient synthesis of new khellactone-type compounds using potassium hydroxide as catalyst via one-pot, three-component reaction
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