Eco-friendly biogenic silver nanoparticles: synthesis, characterization and biological applications

• Published in: International journal of environmental science and technology (Tehran) 2024-07
• Main Authors: Korkmaz, N., Ceylan, Y., İmamoğlu, R., Kısa, D., Şen, F., Karadağ, A.
• Format: Article
• Language: English
• ISSN: 1735-1472; 1735-2630
• DOI: 10.1007/s13762-024-05860-w

Recent developments in nanotechnology and nanoscience in all phases of human life have radically altered the diagnosis, treatment, and prevention of numerous diseases. Silver nanoparticles (Ag-NPs) have been among the most dynamic, and Several metallic nanoparticles developed for biological uses include some beautiful nanomaterials. Ag-NPs have played a pivotal role in nanotechnology and nanoscience, mostly nanomedicine. In this work, Ficus carica leaf extract was utilized to create silver nanoparticles using a straightforward procedure. This study explored the reduction of silver ions by F. carica leaf extract in the solution. UV–Vis spectroscopy, XRD analysis, and STEM characterize prepared biogenic Ag-NPs. Afterward, antibacterial and antibiofilm properties were investigated. The images obtained from STEM analysis surveyed that the NP sizes ranged from 11 to 20 nm. Ag-NPs demonstrated antibacterial and antibiofilm activities against all tested Gram-positive and Gram-negative bacteria strains. It has been indicated that Ag-NPs have inhibitory potency against collagenase activity. Ag-NPs exhibited anticancer activity in the HeLa cell line, and the IC 50 value was calculated as 8.403 μg/mL. In this study, it has been shown that the synthesis method is environmentally friendly, fast, safe, and easy to use.