Endoscopic Optic Nerve Decompression: Indications, Technique, Results

• Published in: Current otorhinolaryngology reports 2019-06, Vol.7 (2), p.153-164
• Main Authors: Welkoborsky, Hans J., Kuestermeyer, Julian, Steinke, Kim V., Paehler, Anja, Deichmueller, Cordula M. C.
• Format: Article
• Language: English
• Subjects: Endoscopic Orbital Surgery (B Bleier; Medicine; Medicine & Public Health; Otorhinolaryngology; Section Editor; Topical Collection on Endoscopic Orbital Surgery
• ISSN: 2167-583X; 2167-583X
• DOI: 10.1007/s40136-019-00235-z

Purpose of Review For decades, treatment of compressive optic nerve neuropathy was conservative and involved the intravenous application of high-dose corticoids, which was combined with nerve growth factors in later years. If surgery was considered, transcranial and transfacial access to the orbital apex and the optic nerve were achieved using classical approaches. Over the past decade, endonasal endoscopic procedures have increasingly come into force, based on favorable experiences with functional endoscopic sinus surgery and as a result of innovative developments in endoscopy and image guidance. The purpose of this review is to address the latest literature in this field with regard to the indications, techniques, results, and complications associated with this procedure. Recent Findings There are basically two approaches for endoscopic optic nerve decompression: the extradural supraorbital “keyhole” approach, which provides access to the optic nerve canal roof and which is usually performed by neurosurgeons, and the endonasal endoscopic approach, which is widely used by otorhinolaryngologists. The development and application of endonasal endoscopic surgery was only possible with extensive knowledge of the topographic anatomy. The most important anatomical landmarks and topography have been described based on either cadaveric or CT scan studies, and include the opticocarotid recess, the distance between the optic nerve canal and the internal carotid artery, the ophthalmic artery, and the length of the optic nerve canal. There are two main indications for endonasal endoscopic optic nerve decompression: (1) traumatic optic nerve neuropathy (TON), and (2) optic nerve neuropathy from non-traumatic causes (nTON), such as tumorous conditions, inflammatory diseases, or idiopathic intracranial hypertension (IIH). In trauma cases, rates of postoperative visual improvement of 40–80% have been reported. Factors influencing the outcome include the severity of the injury, initial visual acuity (light perception or better vs. no light perception), the time interval between trauma and intervention, and the type of injury, such as fracture lines directly through the optic nerve canal or probable avulsion trauma. nTON cases generally have a slightly better prognosis, with vision improvement of 54–100% reported. The procedure should be performed before any optic nerve atrophy can occur. In IIH cases, all major symptoms, including vision loss, headache, visual field deteri