Women and acute kidney injury in myocardial infarction

Background Data on the relationship between gender and acute kidney injury (AKI) in patients with myocardial infarction (MI) undergoing percutaneous coronary intervention (PCI) are conflicting and inconclusive. The contrast volume-to-estimated glomerular filtration rate ratio (CV/GFR) was shown to p...

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Bibliographic Details
Published in:Journal of nephrology 2018-10, Vol.31 (5), p.713-719
Main Authors: Kanic, Vojko, Vollrath, Maja, Kompara, Gregor, Suran, David, Hojs, Radovan
Format: Article
Language:English
Subjects:
Medicine
Medicine & Public Health
Nephrology
Original Article
Urology
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Summary:Background Data on the relationship between gender and acute kidney injury (AKI) in patients with myocardial infarction (MI) undergoing percutaneous coronary intervention (PCI) are conflicting and inconclusive. The contrast volume-to-estimated glomerular filtration rate ratio (CV/GFR) was shown to predict AKI in patients with MI undergoing PCI. We assessed gender-based differences in AKI and evaluated the association between the CV/GFR and AKI in MI patients undergoing PCI. Methods We retrospectively studied 4675 consecutive patients with MI who underwent PCI between January 2007 and December 2015. The incidence of AKI and CV/GFR in men and women were compared. Data were analyzed using descriptive statistics. Results Women suffered more AKI than men [152 (10.5%) women suffered AKI compared to 252 (7.8%) men; p  = 0.003]. After adjustment for potential confounders, female gender was identified as an independent predictive factor for AKI. CV/GFR was higher in women (2.57 ± 1.95 in women vs. 2.25 ± 1.60 in men; p  
ISSN:1121-8428
1724-6059
DOI:10.1007/s40620-018-0504-4