A Review Study of the Impact of Plant Extracts on Viral Infections Like HPV and Cervical Cancer

Purpose Numerous women die annually from cervical cancer, which is one of the most common types of cancer affecting women worldwide. The majority of cases of this cancer are brought on by infection with the human papillomavirus (HPV). As radiotherapy and chemotherapy methods have side effects and da...

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Bibliographic Details
Published in:Indian journal of gynecologic oncology 2024-06, Vol.22 (2), Article 46
Main Authors: Döğüş, Yusuf, Daemi, Amin, Mortezania, Zohreh, Hosseini, Seyyedeh Touran, Yousefi, Yavar, Yönden, Zafer, Atcı, Sertap
Format: Article
Language:English
Subjects:
Medicine
Medicine & Public Health
Oncology
Review Article
Surgical Oncology
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Summary:Purpose Numerous women die annually from cervical cancer, which is one of the most common types of cancer affecting women worldwide. The majority of cases of this cancer are brought on by infection with the human papillomavirus (HPV). As radiotherapy and chemotherapy methods have side effects and damage healthy cells, natural products, mainly plant extracts, have been investigated for cancer treatment. Methods This review study analyzed the effects of plant extracts and remedies on viral infections such as HPV and cervical cancer from 2000 to 2023. Results The results revealed that plant extracts and products had anticancer activity through mechanisms like inducing apoptosis, helping DNA repair, increasing production of anti-tumor enzymes, blocking HPV-assisted transcription factors, and strengthening the immune system. Conclusion Therefore, they can be recommended as a safe herbal drug.
ISSN:2363-8397
2363-8400
DOI:10.1007/s40944-024-00815-y