Methodological study on endogenous calcium absorptivity using rats and 41Ca tracing

Elemental calcium plays an important role in human physiology. In order to study the relationship between Ca-intake, Ca-chemical formulation, and Ca-absorptivity, a balance experiment using a 41Ca tracer technique in SD rats was conducted to measure the endogenous fecal calcium and true absorption o...

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Bibliographic Details
Published in:Nuclear science and techniques 2018-04, Vol.29 (4), p.79-82, Article 56
Main Authors: Zhang, Hui, Dou, Liang, Wang, Xiao-Ming, Mi, Sheng-Quan, Zhao, Qing-Zhang, Jiang, Shan, He, Ming
Format: Article
Language:English
Subjects:
41Ca
absorptivity
Accelerator
calcium
Endogenous
Energy
Hadrons
Heavy Ions
mass
measurement
Nuclear Energy
Nuclear Physics
spectrometry
tracer
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Summary:Elemental calcium plays an important role in human physiology. In order to study the relationship between Ca-intake, Ca-chemical formulation, and Ca-absorptivity, a balance experiment using a 41Ca tracer technique in SD rats was conducted to measure the endogenous fecal calcium and true absorption of calcium. Apparent absorption of calcium was measured as a control to the endogenous calcium labeling experiment. These results show that by using 41Ca labeled endogenous calciumin vivo, researchers could obtain the true calcium absorption data without extrinsic labeling. Therefore, the method was not affected by the chemical structure or type of calcium supplement and might be used in evaluating the absorptivity of marketed calcium supplements.
ISSN:1001-8042
2210-3147
DOI:10.1007/s41365-018-0387-z