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Age and size dependent diagnostic reference levels and achievable doses for 48 types of CT examinations: a multicenter cross-sectional study of one million CT examinations in China

Objective To establish diagnostic reference levels (DRLs) and achievable doses (ADs) of 48 commonly used CT examinations including advanced CT techniques such as dual energy CT (DECT) based on patient age and size in Chinese multicenter cohort with one million CT examinations. Methods Radiation dose...

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Bibliographic Details
Published in:Chinese journal of academic radiology 2024-12, Vol.7 (4), p.367-389
Main Authors: Wu, Shiyao, Zhou, Changsheng, Xu, Yikai, Qiao, Wenjun, Xia, Liming, Li, Yang, Huang, Chao, He, Haoqiang, Deng, Dele, Dai, Wei, Huang, Jin, Zhong, Nengzhi, Yang, Guifen, Zhang, Longjiang, Xie, Chuanmiao, Lu, Guangming
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Language:English
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Summary:Objective To establish diagnostic reference levels (DRLs) and achievable doses (ADs) of 48 commonly used CT examinations including advanced CT techniques such as dual energy CT (DECT) based on patient age and size in Chinese multicenter cohort with one million CT examinations. Methods Radiation dose data on 48 commonly used CT examinations including conventional CT examinations, CT angiography (CTA), and DECT examinations at four Chinese university hospitals between January 2016 and December 2018 were retrospectively collected. For all CT examinations, dose indexes were analyzed based on patient age and size. ADs and DRLs for volume CT dose index (CTDI vol ), dose-length product (DLP), size-specific dose estimate (SSDE) and effective dose (ED) were analyzed. Results 1,001,190 CT examinations were available for dose analysis. The most common examination was non-enhanced chest CT (26.25%) with the age-based CTDI vol AD ranging from 2.50 to 7.66 mGy and DRL from 3.67 to 10.29 mGy. Coronary CTA was the most used CTA (42.19%), with CTDI vol AD ranging from 8.08 to 13.65 mGy and DRL from 11.73 to 22.21 mGy. DECT of extremity was the most used DECT examination (48.24%), with CTDI vol AD ranging from 2.23 to 2.55 mGy and DRL ranged from 2.66 to 4.61 mGy. DRLs and ADs for size-based CTDI vol , DLP, SSDE and ED increased consistently with patient size. Conclusion This multicenter study provided DRLs of 48 commonly used CT examinations including conventional CT examinations, CTA, and DECT examinations based on patient age and size. Further research is required to develop national DRLs to guide CT radiation optimization.
ISSN:2520-8985
2520-8993
DOI:10.1007/s42058-024-00172-x