Caffeoylquinic Acid Derivatives: Chemical Diversity and Effect on the Oxidative Stress-Related Pathologies

Caffeoylquinic acids (CQAs) are a phenolic compounds widely distributed in various plant-derived products. They are formed via reactions of esterification of caffeic and quinic acids, which means that they constitute a group of high structural diversity, the reason why they have received an increasi...

Full description

Saved in:
Bibliographic Details
Published in:Chemistry Africa 2024-10, Vol.7 (8), p.4105-4126
Main Authors: Bejaoui, Afef, M’rabet, Yassine, Boulila, Abdennacer
Format: Article
Language:English
Subjects:
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Inorganic Chemistry
Organometallic Chemistry
Review
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Caffeoylquinic acids (CQAs) are a phenolic compounds widely distributed in various plant-derived products. They are formed via reactions of esterification of caffeic and quinic acids, which means that they constitute a group of high structural diversity, the reason why they have received an increasing interest from medicinal chemists for the search of new therapeutic agents. The intake of CQA enriched aliments have been positively correlated to health benefits since these molecules act as potent antioxidants which make them interesting candidates for the research of novel drugs against oxidative stress-related human pathologies. Recent clinical trials have demonstrated the effectiveness of these molecules in the prevention/treatment of cancer, diabetes, cardiovascular, and inflammatory diseases. In this review, we focus on the progress in CQAs chemistry and we highlight the new insights regarding their biological effect and their bioavailability based on the recent peer-reviewed published works in the most known scientific databases.
ISSN:2522-5758
2522-5766
DOI:10.1007/s42250-024-00985-4