Response Monitoring to Neoadjuvant Chemotherapy in Osteosarcoma Using Dynamic Contrast-Enhanced MR Imaging

To evaluate the dynamic contrast-enhanced MRI parameters for monitoring the neoadjuvant chemotherapy (NAC) response in osteosarcoma prospectively. A total of 19 patients with osteosarcoma were recruited and underwent two dynamic contrast-enhanced MRI (DCE-MRI) examinations before and after chemother...

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Bibliographic Details
Published in:SN comprehensive clinical medicine 2019-05, Vol.1 (5), p.319-327
Main Authors: Zhang, Bu-Tian, Zheng, Qian, Liu, Lin, Zeng, Yan-Ni, Dai, Yi-Meng, Jiang, Jin-Lan, Xue, Kai-ming
Format: Article
Language:English
Subjects:
Imaging
Medicine
Medicine & Public Health
Topical Collection on Imaging
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Summary:To evaluate the dynamic contrast-enhanced MRI parameters for monitoring the neoadjuvant chemotherapy (NAC) response in osteosarcoma prospectively. A total of 19 patients with osteosarcoma were recruited and underwent two dynamic contrast-enhanced MRI (DCE-MRI) examinations before and after chemotherapy. Patients with ≥ 90% tumor necrosis were defined as responders (10 patients), and those
ISSN:2523-8973
2523-8973
DOI:10.1007/s42399-019-00059-4