Association of Serum Fibrinogen and Plasma VEGF Levels with Tumor Characteristics and Treatment Response in Operable Breast Carcinoma

A search for factors predicting the behavior of the tumor, its invasiveness, metastasis, response to treatment, and prognosis is the primary focus of breast cancer research. The objective of the present study was to study the association of fibrinogen and vascular endothelial growth factor (VEGF) wi...

Full description

Saved in:
Bibliographic Details
Published in:SN comprehensive clinical medicine 2022-10, Vol.4 (1), Article 234
Main Authors: Khowal, Hemant Kumar, Yelamanchi, Raghav, Gupta, Nikhil, Goswami, Binita, Jain, Anju, Arora, Mohinder Pal
Format: Article
Language:English
Subjects:
Medicine
Medicine & Public Health
Original Paper
Topical Collection on Surgery
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A search for factors predicting the behavior of the tumor, its invasiveness, metastasis, response to treatment, and prognosis is the primary focus of breast cancer research. The objective of the present study was to study the association of fibrinogen and vascular endothelial growth factor (VEGF) with various parameters of breast carcinoma. A case control was conducted in which fibrinogen, and VEGF levels were compared between cases and controls and also with various characteristics of breast carcinoma such as T stage, lymph node positivity, grade, lymphovascular invasion, and receptor status. The effect of surgery of breast cancer on fibrinogen and VEGF levels was also studied. The levels of fibrinogen and VEGF were significantly higher in cases when compared to controls ( p  
ISSN:2523-8973
2523-8973
DOI:10.1007/s42399-022-01318-7