Chiral separations performed by supercritical fluid chromatography

Supercritical fluid chromatography is an attractive alternative for chiral separations of compounds which are not readily analyzed by gas chromatography. It offers fast separations, high-efficiency, low-temperature analysis and access to a wide range of detectors including the “universal’ flame ioni...

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Bibliographic Details
Published in:Journal of Chromatography A 1994-04, Vol.666 (1), p.381-394
Main Authors: Petersson, P., Markides, K.E.
Format: Article
Language:English
Subjects:
Analytical chemistry
Chemistry
Chromatographic methods and physical methods associated with chromatography
Exact sciences and technology
Other chromatographic methods
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Summary:Supercritical fluid chromatography is an attractive alternative for chiral separations of compounds which are not readily analyzed by gas chromatography. It offers fast separations, high-efficiency, low-temperature analysis and access to a wide range of detectors including the “universal’ flame ionization detector. In this article the state of the art is reviewed. The technique is compared with other chromatographic techniques and the applicability of different chiral stationary phases as well as the choice of experimental conditions is discussed.
ISSN:0021-9673
DOI:10.1016/0021-9673(94)80398-6