Investigation of analysis techniques for complicated NMR relaxation data

Precision NMR relaxation measurements of biological tissue frequently show complex multicomponent behavior. This paper presents methods for generating information about these relaxation spectra even when the original data are nonideal. A variety of acceptable solutions with differing types of simpli...

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Bibliographic Details
Published in:Journal of magnetic resonance (1969) 1991-11, Vol.95 (2), p.221-234
Main Authors: Whittall, Kenneth P, Bronskill, Michael J, Henkelman, R.Mark
Format: Article
Language:English
Subjects:
Atomic and molecular physics
Exact sciences and technology
Molecular properties and interactions with photons
Nuclear resonance and relaxation
Physics
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Summary:Precision NMR relaxation measurements of biological tissue frequently show complex multicomponent behavior. This paper presents methods for generating information about these relaxation spectra even when the original data are nonideal. A variety of acceptable solutions with differing types of simplicity are investigated. Ways of inferring trends in relaxation spectra that are independent of the particular analysis model are illustrated with examples using linear programming techniques. The question of the number, spacing, and signal-to-noise ratio of data for optimal experiments is also addressed.
ISSN:0022-2364
1557-8968
DOI:10.1016/0022-2364(91)90213-D