Soluble ternary complex of poly-4-vinylpyridine, bovine serum albumin and copper

The interaction between poly-4-vinylpyridine and bovine serum albumin in an acidic medium, in which bivalent copper ions participate, has been investigated. It has been shown that they form a soluble ternary complex over a wide range of the ratio between the components. Light-scattering, sedimentati...

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Bibliographic Details
Published in:Polymer science USSR 1981, Vol.23 (2), p.299-304
Main Authors: Mustafayev, M.I., Kabanov, V.A.
Format: Article
Language:English
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Summary:The interaction between poly-4-vinylpyridine and bovine serum albumin in an acidic medium, in which bivalent copper ions participate, has been investigated. It has been shown that they form a soluble ternary complex over a wide range of the ratio between the components. Light-scattering, sedimentation rate and viscometry have been used to establish that the actual particle of the ternary polycomplex is represented by an associate that includes, as subunits, six or seven polycations with which The albumin globules are linked by means of copper ions. It is shown that te particles of the soluble ternary complex are very compact.
ISSN:0032-3950
1878-268X
DOI:10.1016/0032-3950(81)90169-6