A solid phase approach to quinolones using the DIVERSOMER ® technology

The first example of a library of the quinolone antibacterial agents prepared by solid phase organic synthesis is described. Results of these studies and the parallel synthesis, isolation, purification and analysis of eight quinolones are discussed. The first example of a library of the quinolone an...

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Bibliographic Details
Published in:Tetrahedron letters 1996-07, Vol.37 (27), p.4815-4818
Main Authors: MacDonald, Alasdair A, DeWitt, Sheila H, Hogan, Eleonora M, Ramage, Robert
Format: Article
Language:English
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Summary:The first example of a library of the quinolone antibacterial agents prepared by solid phase organic synthesis is described. Results of these studies and the parallel synthesis, isolation, purification and analysis of eight quinolones are discussed. The first example of a library of the quinolone antibacterial agents prepared by solid phase organic synthesis is described. Results of these studies and the parallel synthesis, isolation, purification and analysis of eight quinolones are discussed.
ISSN:0040-4039
1873-3581
DOI:10.1016/0040-4039(96)00944-6