Palladium-catalyzed asymmetric 1,3-dipolar cycloaddition of nitrones to olefins

Asymmetric 1,3-dipolar cycloaddition of nitrone 2 to olefin 1 was catalyzed by chiral phosphine - palladium complexes to give isoxazolidine 3 in high yield with high enantioselectivity up to 91% ee. Asymmetric 1,3-dipolar cycloaddition of nitrone 2 with olefin 1 was catalyzed by a chiral phosphine-p...

Full description

Saved in:
Bibliographic Details
Published in:Tetrahedron letters 1996-08, Vol.37 (33), p.5947-5950
Main Authors: Hori, Kazushige, Kodama, Hidehiko, Ohta, Tetsuo, Furukawa, Isao
Format: Article
Language:English
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Asymmetric 1,3-dipolar cycloaddition of nitrone 2 to olefin 1 was catalyzed by chiral phosphine - palladium complexes to give isoxazolidine 3 in high yield with high enantioselectivity up to 91% ee. Asymmetric 1,3-dipolar cycloaddition of nitrone 2 with olefin 1 was catalyzed by a chiral phosphine-palladium complex to give isoxazolidine 3 in high yield with high enantioselectivity up to 91% ee. [Display omitted]
ISSN:0040-4039
1873-3581
DOI:10.1016/0040-4039(96)01284-1