Fluvoxamine and lithium in long-term treatment of unipolar subjects with high recurrence rate

We prolonged from 24 to 36 months a follow-up study of unipolar subjects with a high probability of recurrence treated with fluvoxamine ( n = 32) or lithium ( n = 32). During the extra observation period, two patients developed mania and were excluded from the study. There were no further recurrence...

Full description

Saved in:
Bibliographic Details
Published in:Journal of affective disorders 1996-04, Vol.38 (1), p.67-69
Main Authors: Franchini, Linda, Zanardi, Raffaella, Gasperini, Mariangela, Perez, Jorge, Smeraldi, Enrico
Format: Article
Language:English
Subjects:
Adult
Antidepressive Agents, Second-Generation - adverse effects
Antidepressive Agents, Second-Generation - therapeutic use
Antidepressive Agents, Tricyclic - adverse effects
Antidepressive Agents, Tricyclic - therapeutic use
Antimanic Agents - adverse effects
Antimanic Agents - therapeutic use
Biological and medical sciences
Bipolar Disorder - diagnosis
Bipolar Disorder - drug therapy
Bipolar Disorder - psychology
Depressive Disorder - diagnosis
Depressive Disorder - drug therapy
Depressive Disorder - psychology
Female
Fluvoxamine
Fluvoxamine - adverse effects
Fluvoxamine - therapeutic use
Follow-Up Studies
Humans
Lithium
Lithium - adverse effects
Lithium - therapeutic use
Long-term treatment
Male
Medical sciences
Neuropharmacology
Pharmacology. Drug treatments
Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease)
Psychology. Psychoanalysis. Psychiatry
Psychopharmacology
Recurrence
Selective serotonin reuptake inhibitor
Treatment Outcome
Tricyclic
Unipolar
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:We prolonged from 24 to 36 months a follow-up study of unipolar subjects with a high probability of recurrence treated with fluvoxamine ( n = 32) or lithium ( n = 32). During the extra observation period, two patients developed mania and were excluded from the study. There were no further recurrences in either the lithium or the fluvoxamine group. In our sample, previous prescriptions of tricyclics seem to predict a worse prognosis.
ISSN:0165-0327
1573-2517
DOI:10.1016/0165-0327(95)00095-X