Opto-thermal in-vivo monitoring of structural breakdown of an emulsion sunscreen on skin

Opto-thermal transient emission radiometry (OTTER) is showing promise as a powerful and convenient means for in-vivo monitoring of human or animal skin properties and surface concentrations of topically applied substances, such as drugs and cosmetics. The technique is also sensitive to structural ph...

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Bibliographic Details
Published in:Clinical materials 1990, Vol.5 (2), p.271-278
Main Authors: Imhof, R.E., Whitters, C.J., Birch, D.J.S.
Format: Article
Language:English
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Summary:Opto-thermal transient emission radiometry (OTTER) is showing promise as a powerful and convenient means for in-vivo monitoring of human or animal skin properties and surface concentrations of topically applied substances, such as drugs and cosmetics. The technique is also sensitive to structural phase transitions, for example in emulsion sun crêmes, if the laser pulse energy is sufficient to heat near-surface material momentarily above a phase transition temperature. This paper reports the first in-vivo observations of the break-up of physical structure of a sun creme on skin, which was found to occur on a time scale short compared with its mean residence time.
ISSN:0267-6605
DOI:10.1016/0267-6605(90)90026-R