Recovery of erythromycin by a liquid membrane

A supported liquid membrane technique was applied for extraction of erythromycin A from its dilute slightly alkaline aqueous solutions. 1-decanol was used as an intermediate (membrane) phase and a buffered acidic aqueous solution to strip the organic membrane. The antibiotic distribution coefficient...

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Bibliographic Details
Published in:Journal of membrane science 1996-04, Vol.112 (2), p.209-217
Main Authors: Kawasaki, J., Egashira, R., Kawai, T., Hara, H., Boyadzhiev, L.
Format: Article
Language:English
Subjects:
Antibiotic extraction
Antibiotic recovery
Biological and medical sciences
Biotechnology
Erythromycin
Erythromycin extraction
Fundamental and applied biological sciences. Psychology
Liquid membrane
Methods. Procedures. Technologies
Others
Pertraction
Various methods and equipments
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Summary:A supported liquid membrane technique was applied for extraction of erythromycin A from its dilute slightly alkaline aqueous solutions. 1-decanol was used as an intermediate (membrane) phase and a buffered acidic aqueous solution to strip the organic membrane. The antibiotic distribution coefficient between the membrane used and the feed was found to be 122, providing relatively high solute fluxes across the membrane, although the transfer resistance remains in the filled membrane pores. It was shown that due to existing equilibrium between the protonised and non-protonised forms of the solute, the antibiotic can be completely transferred and concentrated in the receiving, low pH solution.
ISSN:0376-7388
1873-3123
DOI:10.1016/0376-7388(95)00282-0