A multicentre study to introduce naltrexone for opiate dependence in Spain

A multicentre prospective study was performed in eight centres in Spain in order to assess the usefulness of naltrexone in the treatment of opiate dependents and abusers (113 dependents and 37 abusers) non-selected in terms of social class or professional skill. The fundamental criterion for evaluat...

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Bibliographic Details
Published in:Drug and alcohol dependence 1989-04, Vol.23 (2), p.117-121
Main Authors: the Spanish Study Group in Drug Addiction, García-Alonso, F., Gutierrez, M., San, L., Bedate, J., Forteza-Rei, J., Rodríguez-Artalejo, F., Palop, R., López-Alvarez, M., de los Cobos, J.C.Férez, Cami, J.
Format: Article
Language:English
Subjects:
Adult
Biological and medical sciences
Combined Modality Therapy
Drug addictions
Female
Humans
Male
Medical sciences
MMPI
naltrexone
Naltrexone - adverse effects
Naltrexone - therapeutic use
Narcotics
opiate dependence
Opioid-Related Disorders - drug therapy
Opioid-Related Disorders - therapy
Prospective Studies
Psychotherapy
Psychotherapy, Group
Spain
Substance-Related Disorders - therapy
Toxicology
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Summary:A multicentre prospective study was performed in eight centres in Spain in order to assess the usefulness of naltrexone in the treatment of opiate dependents and abusers (113 dependents and 37 abusers) non-selected in terms of social class or professional skill. The fundamental criterion for evaluation of clinical outcome was the retention rate. At 6 months this parameter was 40%, i.e. higher than any previously reported for non-selected patients. The adverse effects were mild and did not lead to therapeutic failures. Non-pharmacological factors may have contributed to the good clinical results obtained.
ISSN:0376-8716
1879-0046
DOI:10.1016/0376-8716(89)90016-1