Thermospray liquid chromatography—mass spectrometry with a quadrupole ion trap mass spectrometer

A thermospray ion source using corona discharge ionization was interfaced to a quadrupole ion trap mass spectrometer via a multi-element lens system. Ions were injected into the trap periodically where they were stabilized by collisions with helium bath gas. Mass spectra were recorded on the trapped...

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Bibliographic Details
Published in:Journal of chromatography. Biomedical applications 1991-01, Vol.562 (1), p.3-11
Main Authors: Kaiser, Raymond E., Williams, Jon D., Lammert, Stephen A., Graham Cooks, R., Zakett, Don
Format: Article
Language:English
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Summary:A thermospray ion source using corona discharge ionization was interfaced to a quadrupole ion trap mass spectrometer via a multi-element lens system. Ions were injected into the trap periodically where they were stabilized by collisions with helium bath gas. Mass spectra were recorded on the trapped ions using the mass-selective instability scan mode. Data are shown for a peptide and a nucleoside and the effects of some experimental variables on the spectra are explored.
ISSN:0378-4347
DOI:10.1016/0378-4347(91)80559-U