Antibodies that react with the capsular polysaccharide of Vibrio vulnificus are detectable in infected patients, and in persons without known exposure to the organism

In serious infections with Vibrio vulnificus, IgG antibodies to the capsular polysaccharide of the infecting strain were demonstrable in patient serum. It was not possible to show that persons with probable increased exposure to V. vulnificus (shellfish industry workers) had increased levels of anti...

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Bibliographic Details
Published in:Diagnostic microbiology and infectious disease 1996-03, Vol.24 (3), p.165-167
Main Authors: Fiore, Anthony, Hayat, Unaiza, Wasserman, Steven S., Wright, Anita, Bush, C.Allen, Morris, J.Glenn
Format: Article
Language:English
Subjects:
Analysis of the immune response. Humoral and cellular immunity
Antibodies, Bacterial - blood
Antibody production
Bacteremia - immunology
Biological and medical sciences
Capsid - immunology
Cross Reactions
Enzyme-Linked Immunosorbent Assay
Fundamental and applied biological sciences. Psychology
Fundamental immunology
Humans
Immunobiology
Occupational Exposure
Polysaccharides, Bacterial - immunology
Vibrio - immunology
Vibrio - isolation & purification
Vibrio Infections - immunology
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Summary:In serious infections with Vibrio vulnificus, IgG antibodies to the capsular polysaccharide of the infecting strain were demonstrable in patient serum. It was not possible to show that persons with probable increased exposure to V. vulnificus (shellfish industry workers) had increased levels of antibodies to any one of three capsular types tested when compared with persons who would be expected to have had minimal exposure to the organism (Seventh Day Adventists). Antibodies that reacted with the capsular polysaccharides were demonstrable in persons without a history of V. vulnificus infection, suggesting that cross-reacting antibodies are present in the general population.
ISSN:0732-8893
1879-0070
DOI:10.1016/0732-8893(96)00020-X