Echocardiographic characterization of the improvement in right ventricular function in patients with severe pulmonary hypertension after single-lung transplantation

Objectives. This study was designed to characterize immediate, early and long-term changes in right ventricular structure and function, as defined by two-dimensional and Doppler echocardiography, after single-lung transplantation in patients with severe pulmonary hypertension. Bacground. Single-lung...

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Bibliographic Details
Published in:Journal of the American College of Cardiology 1993-10, Vol.22 (4), p.1170-1174
Main Authors: Ritchie, Michael, Waggoner, Alan D., Dávila-román, Víctor G., Barzilai, Benico, Trulock, Elbert P., Eisenberg, Paul R.
Format: Article
Language:English
Subjects:
Biological and medical sciences
Cardiac Catheterization
Diastole
Echocardiography
Female
Follow-Up Studies
Hemodynamics
Humans
Hypertension, Pulmonary - complications
Hypertension, Pulmonary - diagnostic imaging
Hypertension, Pulmonary - pathology
Hypertension, Pulmonary - physiopathology
Lung Transplantation - physiology
Male
Medical sciences
Postoperative Complications - diagnostic imaging
Postoperative Complications - pathology
Postoperative Complications - physiopathology
Severity of Illness Index
Stroke Volume
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Surgery of the respiratory system
Systole
Time Factors
Tricuspid Valve Insufficiency - complications
Tricuspid Valve Insufficiency - diagnostic imaging
Tricuspid Valve Insufficiency - physiopathology
Ventricular Function, Right
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Summary:Objectives. This study was designed to characterize immediate, early and long-term changes in right ventricular structure and function, as defined by two-dimensional and Doppler echocardiography, after single-lung transplantation in patients with severe pulmonary hypertension. Bacground. Single-lung transplantation has recently been shown to dramatically improve hemodynamics in patients with primary pulmonary hypertension who had unsuccessful medical therapy. Method. Fourteen patients with severe pulmonary hypertension who underwent single-lung transplantation were studied with transthoracic and transesophageal two-dimensional and Doppler echocardiography. Right ventricular dimensions were measured in the apical four-chamber view. Right ventricular ejection and acceleration times and peak velocity of tricuspid regurgitation were measured by Doppler study. Results of right heart catheterization were available early (
ISSN:0735-1097
1558-3597
DOI:10.1016/0735-1097(93)90433-2