Characterization of human exposure to ambient levels of benzene using pulmonary ‘wash-out’ data

The authors use β-phase pulmonary clearance data in conjunction with a pharmacokinetic model to estimate average background ambient level benzene exposure and resultant body burden. The pharmacokinetic model is also used to estimate the absorbed dose of benzene for cigarette smoking.

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Bibliographic Details
Published in:Atmospheric environment 1991, Vol.25 (8), p.1643-1647
Main Authors: Travis, Curtis C., Craig, Peter H., Bowers, John C.
Format: Article
Language:English
Subjects:
Benzene
Biological and medical sciences
biomonitoring
Chemical and industrial products toxicology. Toxic occupational diseases
Medical sciences
pharmacokinetics
Toxicology
Various organic compounds
wash-out data
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Description
Summary:The authors use β-phase pulmonary clearance data in conjunction with a pharmacokinetic model to estimate average background ambient level benzene exposure and resultant body burden. The pharmacokinetic model is also used to estimate the absorbed dose of benzene for cigarette smoking.
ISSN:0960-1686
0004-6981
DOI:10.1016/0960-1686(91)90022-Y