C-Attached aminoalkylindoles: potent cannabinoid mimetics

Aminoalkylindoles (AAIs) with potent cannabinoid agonist activity have been synthesized where the aminoalkyl chain is attached to the indole ring via a carbon atom of the cyclic amine. Aminoalkylindoles (AAIs) with potent cannabinoid agonist activity ( 30) have been synthesized where the aminoalkyl...

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Bibliographic Details
Published in:Bioorganic & medicinal chemistry letters 1996-01, Vol.6 (1), p.17-22
Main Authors: D'Ambra, Thomas E., Eissenstat, Michael A., Abt, Jeffrey, Ackerman, James H., Bacon, Edward R., Bell, Malcolm R., Carabateas, Philip M., Josef, Kurt A., Kumar, Virendra, Weaver, John D., Arnold, Renee, Casiano, Frances M., Chippari, Susan M., Haycock, Dean A., Kuster, Joan E., Luttinger, Daniel A., Stevenson, Joan I., Ward, Susan J., Hill, W.Adam, Khanolkar, Atmaram, Makriyannis, Alexandros
Format: Article
Language:English
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Summary:Aminoalkylindoles (AAIs) with potent cannabinoid agonist activity have been synthesized where the aminoalkyl chain is attached to the indole ring via a carbon atom of the cyclic amine. Aminoalkylindoles (AAIs) with potent cannabinoid agonist activity ( 30) have been synthesized where the aminoalkyl chain is attached to the indole ring via a carbon atom of the cyclic amine.
ISSN:0960-894X
1464-3405
DOI:10.1016/0960-894X(95)00560-G