Two step synthesis of 1,3-acetylated, -butyroylated and -caproylated triglycerides from a microorganism oil rich in Docosahexaenoic Acid (DHA)

1,3-acetylated, -butyroylated and -caproylated triglycerides were prepared in two steps by hemisynthesis from microorganism triglycerides rich in DHA. The triglycerides were first enzymatically transesterified into 2-monoacyl-glycerols which were then acylated with saturated short acid derivatives w...

Full description

Saved in:
Bibliographic Details
Published in:Bioorganic & medicinal chemistry letters 1996-02, Vol.6 (4), p.345-348
Main Authors: Bayon, Yves, Dolmazon, René
Format: Article
Language:English
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:1,3-acetylated, -butyroylated and -caproylated triglycerides were prepared in two steps by hemisynthesis from microorganism triglycerides rich in DHA. The triglycerides were first enzymatically transesterified into 2-monoacyl-glycerols which were then acylated with saturated short acid derivatives without significant migration of the β-long chain fatty acyl groups to the α position. Title compounds were prepared in two steps by hemi-synthesis from natural oil rich in DHA.
ISSN:0960-894X
1464-3405
DOI:10.1016/0960-894X(96)00020-0