Gamma-ray irradiation, autoclave and ethylene oxide sterilization to thermosetting polyurethane: Sterilization to polyurethane

Thermosetting polyurethane (PU) is widely used in a large variety of medical devices. 4,4′-methylenedianiline (MDA) was produced from PU by sterilization and it was studied for the relationship between urethane components or polymer characteristics and formation of MDA upon sterilization, using the...

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Bibliographic Details
Published in:Radiation physics and chemistry (Oxford, England : 1993) England : 1993), 1995-09, Vol.46 (3), p.377-381
Main Authors: Hirata, Noriko, Matsumoto, Ken-Ichi, Inishita, Takashi, Takenaka, Yoshinori, Suma, Yasunori, Shintani, Hideharu
Format: Article
Language:English
Subjects:
Applied sciences
Biological and medical sciences
Exact sciences and technology
Genital system. Mammary gland
Medical sciences
Physical properties
Polymer industry, paints, wood
Properties and testing
Radiation influence
Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)
Technology of polymers
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Summary:Thermosetting polyurethane (PU) is widely used in a large variety of medical devices. 4,4′-methylenedianiline (MDA) was produced from PU by sterilization and it was studied for the relationship between urethane components or polymer characteristics and formation of MDA upon sterilization, using the commercially available dialyzers fabricated with different combination of isocyanate and polyol. We confirmed that the molecular-weight of polyol influenced the production of MDA upon sterilization.
ISSN:0969-806X
1879-0895
DOI:10.1016/0969-806X(94)00134-6