The use of human immunodeficiency virus postexposure prophylaxis after successful artificial insemination

A case is reported of a woman who was exposed to human immunodeficiency virus through self-insemination. She was artificially inseminated with fresh semen obtained from a gay man in whom HIV seroconversion was taking place. Postexposure prophylaxis with antiretrovirals was initiated 10 days later, a...

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Bibliographic Details
Published in:American journal of obstetrics and gynecology 1999-09, Vol.181 (3), p.760-761
Main Authors: Bloch, Mark, Carr, Andrew, Vasak, Eva, Cunningham, Phillip, Smith, Don
Format: Article
Language:English
Subjects:
Adult
Antibiotics. Antiinfectious agents. Antiparasitic agents
antiretrovirals
Antiviral agents
Antiviral Agents - therapeutic use
artificial insemination
Biological and medical sciences
Birth control
Female
Gynecology. Andrology. Obstetrics
HIV Infections - prevention & control
HIV Infections - transmission
HIV Seropositivity
Human immunodeficiency virus
Humans
Indinavir - therapeutic use
Insemination, Artificial, Heterologous
Lamivudine - therapeutic use
Male
Medical sciences
Pharmacology. Drug treatments
Pregnancy
prophylaxis
Sterility. Assisted procreation
Tissue Donors
Tropical medicine
Zidovudine - therapeutic use
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Summary:A case is reported of a woman who was exposed to human immunodeficiency virus through self-insemination. She was artificially inseminated with fresh semen obtained from a gay man in whom HIV seroconversion was taking place. Postexposure prophylaxis with antiretrovirals was initiated 10 days later, and despite successful conception, HIV infection was not established. A healthy male infant was subsequently delivered with no obvious toxicity related to medication. (Am J Obstet Gynecol 1999;181:760-1.)
ISSN:0002-9378
1097-6868
DOI:10.1016/S0002-9378(99)70529-6