Naphthyldiazoalkanes as derivatizing agents for the high-performance liquid chromatographic detection of fatty acids

The use of naphthyldiazoalkanes as derivatizing agents in the h.p.l.c. separation of fatty acids from C 10 to C 18 is described. Esterification is relatively rapid under mild conditions, and the progress of the reaction can be monitored by the color changes. Derivatization by 1-naphthyldiazomethane...

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Bibliographic Details
Published in:Analytica chimica acta 1979-08, Vol.109 (1), p.61-66
Main Authors: Matthees, Duane P., Purdy, William C.
Format: Article
Language:English
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Summary:The use of naphthyldiazoalkanes as derivatizing agents in the h.p.l.c. separation of fatty acids from C 10 to C 18 is described. Esterification is relatively rapid under mild conditions, and the progress of the reaction can be monitored by the color changes. Derivatization by 1-naphthyldiazomethane or 1-(2-naphthyl)-diazoethane is recommended; 1-(4-biphenylyl)-diazoethane shows some promise in the separation of short-chain fatty acids. The fatty acid profiles of butterfat, margarine, and castor oil are reported.
ISSN:0003-2670
1873-4324
DOI:10.1016/S0003-2670(01)84227-6