Selective inhibition of interleukin-8-induced neutrophil chemotaxis by ketoprofen isomers 11Abbreviations: NSAIDs, non-steroidal anti-inflammatorydrugs; COX, cyclooxygenase; PG, prostaglandin; PMN, humanpolymorphonuclear leukocyte; IL-8, interleukin-8;[Ca2+]i, intracellular calcium concentration;MAPK, mitogen-activated protein kinases; fMLP,N-formyl-methionyl-leucyl-phenylalanine; ERK, extracellular signalregulated kinase; C5a, fifth component of complement; MCP-1, monocytechemotactic protein-1;

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Bibliographic Details
Published in:Biochemical pharmacology 2001-06, Vol.61 (11), p.1429-1437
Main Authors: Bizzarri, Cinzia, Pagliei, Sabrina, Brandolini, Laura, Mascagni, Patrizia, Caselli, Gianfranco, Transidico, Pietro, Sozzani, Silvano, Bertini, Riccardo
Format: Article
Language:English
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ISSN:0006-2952
DOI:10.1016/S0006-2952(01)00610-4