Enhanced activity of antisense phosphorothioate oligos against Leishmania amastigotes: augmented uptake of oligo, ribonuclease H activation, and efficient target intervention under altered growth conditions11Abbreviations: S-oligo, phosphorothioate oligodeoxyribonucleotide; ASM, anti-miniexon S-oligo; SSM, S-oligo complementary and anti-parallel to ASM; LUAS, anti-luciferase S-oligo; LUS, S-oligo complementary and anti-parallel to LUAS; MBSA, maleylated BSA; DMPC, dimyristoyl phosphatidylcholine

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Published in:Biochemical pharmacology 2001-09, Vol.62 (5), p.569-580
Main Authors: Mishra, Manjari, Porter-Kelley, Johanna M, Singh, Pramod K, Bennett, Jabbar R, Chaudhuri, Gautam
Format: Article
Language:English
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ISSN:0006-2952
DOI:10.1016/S0006-2952(01)00695-5