Compact 2-D graphical representation of DNA

We present a novel 2-D graphical representation for DNA sequences which has an important advantage over the existing graphical representations of DNA in being very compact. It is based on: (1) use of binary labels for the four nucleic acid bases, and (2) use of the ‘worm’ curve as template on which...

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Bibliographic Details
Published in:Chemical physics letters 2003-05, Vol.373 (5), p.558-562
Main Authors: Randić, Milan, Vračko, Marjan, Zupan, Jure, Novič, Marjana
Format: Article
Language:English
Subjects:
Analytical, structural and metabolic biochemistry
Biological and medical sciences
DNA, RNA
Fundamental and applied biological sciences. Psychology
General aspects
General aspects, investigation methods
Molecular biophysics
Nucleic acids
Structure and bonding
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Summary:We present a novel 2-D graphical representation for DNA sequences which has an important advantage over the existing graphical representations of DNA in being very compact. It is based on: (1) use of binary labels for the four nucleic acid bases, and (2) use of the ‘worm’ curve as template on which binary codes are placed. The approach is illustrated on DNA sequences of the first exon of human β-globin and gorilla β-globin.
ISSN:0009-2614
1873-4448
DOI:10.1016/S0009-2614(03)00639-0