Medical treatment of a grossly enlarged adenomyotic uterus with the levonorgestrel-releasing intrauterine system

Adenomyosis is an important cause of menorrhagia. Besides hysterectomy, the treatment options for adenomyosis have been limited. Presented here is the successful treatment of adenomyosis in a woman presenting with menorrhagia, dysmenorrhea, and an enlarging uterus, for whom conservative therapy init...

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Bibliographic Details
Published in:Contraception (Stoneham) 1999-09, Vol.60 (3), p.173-175
Main Authors: Fong, Yoke-Fai, Singh, Kuldip
Format: Article
Language:English
Subjects:
adenomyosis
Adult
Biological and medical sciences
Contraindications
Drug Implants
dysmenorrhea
Endometriosis - complications
Endometriosis - drug therapy
Endometriosis - pathology
Female
Genital system. Reproduction
Humans
Hysterectomy
Levonorgestrel - administration & dosage
Levonorgestrel - adverse effects
Levonorgestrel - therapeutic use
LNG-IUS
Malignant Hyperthermia
Medical sciences
menorrhagia
Menorrhagia - etiology
Pharmacology. Drug treatments
Progesterone Congeners - administration & dosage
Progesterone Congeners - adverse effects
Progesterone Congeners - therapeutic use
Uterine Hemorrhage - chemically induced
Uterus - drug effects
Uterus - pathology
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Summary:Adenomyosis is an important cause of menorrhagia. Besides hysterectomy, the treatment options for adenomyosis have been limited. Presented here is the successful treatment of adenomyosis in a woman presenting with menorrhagia, dysmenorrhea, and an enlarging uterus, for whom conservative therapy initiated with mefenamic acid was unsatisfactory. The patient had insertion of the levonorgestrel-releasing intrauterine system (LNG-IUS). A marked decrease in uterine size occurred within 12 months of insertion accompanied by resolution of the menorrhagia and dysmenorrhea. Thus, the LNG-IUS is a viable option and represents a real advance in the treatment of adenomyosis.
ISSN:0010-7824
1879-0518
DOI:10.1016/S0010-7824(99)00075-X