4474 Prognostics factors of death in ischemic colitis

• Published in: Gastrointestinal endoscopy 2000-04, Vol.51 (4), p.AB145-AB145
• Main Authors: Nunes, Amadeu Cr, Souto, Paulo, Amaro, Pedro, Ribeiro, Bernardino N., Macoas, Fernanda, Rosa, Albano, Pimenta, Isidoro, Freitas, Diniz
• Format: Article
• Language: English
• ISSN: 0016-5107; 1097-6779
• DOI: 10.1016/S0016-5107(00)14321-4

BACKGROUND & AIMS: Ischemic colitis (IC) is considered a disease of elderly patients who have associated diseases. The aim of this study was to evaluate the mortality prognostic factors in patients with IC. PATIENTS AND METHODS: Analysis of 66 consecutive patients (30 men and 36 women) with this disease. We evaluated clinical, analytic, endoscopic, histologic and evolutionary data. Odds Ratio (OR) and the χ2test were used. RESULTS: The patients age ranged from 49 to 94 years (mean : 73 years). Mean hospitalization was 15±12 days. Patients presented mainly with hematochezia (97 %) and abdominal pain (74 %). Co-morbility were present in 56 of 66 patients (85 %). Fourteen of 66 patients (22 %) were found to have more than two segments affected. The majority of lesions occured in the sigmoid colon (89 % cases). The severity endoscopic features (Ann. Gastroentérol. Hépatol., 1990, 26 : 181-183) was grade I (29 %), grade II (63 %) and grade III (8 %). Ten of 66 patients (15 %) presented colonic strictures. Five of 66 patients (8 %) required surgery. Seven patients (11 %) died. The death was significantly associated with LDH>600U/l (OR=26,2; IC=2,9-240), >2 segments of colon affected (OR=37,5; IC=3,8-353,9) and subocclusion (OR=23,2; IC=1,8-302,7). Normal LDH was associated with favourable evolution (OR=0,04; IC=0-0,35). CONCLUSIONS: Increased LDH (>600U/l), extension of colitis and subocclusion were significant prognostics factors of death.