Binding study of 3h-Ro 22-1319, a new potent antipsychotic drug-evidence for a D2 antagonist

Ro 22-1319 (2,6-dimethyl-3-ethyl-4i4a/5,6,7,8,8a,9-octahydro-4a,8a-trans-lH-pyrrolo[2,3-g]isoquinolin-4-one,HCl) is a new potent antipsychotic drug, supposingly with a weak cataleptogenic activity and a lack of autonomic liability (J. Med. Chem. 24, 1026, 1981).

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Bibliographic Details
Published in:Japanese journal of pharmacology 1983, Vol.33, p.197-197
Main Authors: Nakajima, Tohru, Iwata, Kumiko, Kuruma, Isami, Nakamura, Keiji
Format: Article
Language:English
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Summary:Ro 22-1319 (2,6-dimethyl-3-ethyl-4i4a/5,6,7,8,8a,9-octahydro-4a,8a-trans-lH-pyrrolo[2,3-g]isoquinolin-4-one,HCl) is a new potent antipsychotic drug, supposingly with a weak cataleptogenic activity and a lack of autonomic liability (J. Med. Chem. 24, 1026, 1981).
ISSN:0021-5198
1347-3506
DOI:10.1016/S0021-5198(19)60527-5