The number of stenotic coronary arteries and passive smoking exposure from husband in lifelong non-smoking women in Xi'an, China

• Published in: Atherosclerosis 1996-12, Vol.127 (2), p.229-238
• Main Authors: He, Yao, Lam, Tai Hing, Li, Liang Shou, Li, Lam Sun, Du, Ri Ying, Jia, Guo Liang, Huang, Jiu Yi, Zheng, Jiang Sun
• Format: Article
• Language: English
• Subjects: Adult; Aged; Angiography; Arteriosclerosis; Biological and medical sciences; Cardiology. Vascular system; Case-Control Studies; China - epidemiology; Coronary; Coronary Angiography; Coronary Disease - diagnostic imaging; Coronary Disease - epidemiology; Coronary Disease - etiology; Coronary heart disease; Environmental tobacco smoke; Epidemiologic methods; Extent of coronary disease; Female; Heart; Humans; Incidence; Male; Medical sciences; Middle Aged; Odds Ratio; Regression Analysis; Retrospective Studies; Single-Blind Method; Spouses; Tobacco Smoke Pollution - adverse effects
• ISSN: 0021-9150; 1879-1484
• DOI: 10.1016/S0021-9150(96)05960-6

The relationship between the number of stenotic coronary arteries and passive smoking exposure from the husband was examined in a retrospective study of 78 cases with stenotic coronary arteries and 83 controls with normal coronary arteries. All the 161 subjects were examined by coronary arteriography and were Chinese women who had never smoked cigarettes (i.e. lifelong non-smokers). The Pearson's and Spearman's correlation coefficients between the number of stenotic coronary arteries and passive smoking exposure indices were 0.27–0.29 and 0.25–0.28 (all with P < 0.01), respectively. The linear prediction equations from multiple regression analysis showed that passive smoking exposure, after adjustment for other major risk factors, was a significant predictive variable for the number of stenotic coronary arteries. The multiple response logistic regression model was used to estimate the odds ratio of stenotic coronary arteries for passive smoking exposure categories. The crude and adjusted odds ratios showed that the number of stenotic arteries increased with the amount of exposure to passive smoking from the husband. These results provide new evidence to support that passive smoking is causally associated with coronary heart disease.