Development and practical utilization of a linear spectrodensitometer

The development of a linear detector system for the in situ quantitation of thin-layer chromatograms indicates the general applicability of spectrodensitometry, comparable to that of gas-liquid chromatography and liquid column chromatography. There are general requirements to meet, however, regardin...

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Bibliographic Details
Published in:Journal of Chromatography A 1976-01, Vol.123 (1), p.23-32
Main Author: Treiber, Laszlo R.
Format: Article
Language:English
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Summary:The development of a linear detector system for the in situ quantitation of thin-layer chromatograms indicates the general applicability of spectrodensitometry, comparable to that of gas-liquid chromatography and liquid column chromatography. There are general requirements to meet, however, regarding chemical methodology and instrumentation, before this technique may be successfully used. A commercially available instrument modified in our laboratories has shown high sensitivity, reliability, versatility, and short analysis times in biological applications and in the monitoring of organic reactions during synthetic work. Statistical calculations indicate that the construction of an automatic linear spectrodensitometer is now feasible. Some predictions appear to be realistic on the basis of the statistical values.
ISSN:0021-9673
DOI:10.1016/S0021-9673(00)81098-5