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Liquid chromatograph—mass spectrometer—computer analytical systems

Atmospheric pressure ionization (API) mass spectrometry is a novel form of mass spectrometry in which ions are generated in a reaction chamber external to the low-pressure region of a quadrupole mass spectrometer. Using this ionization technique a liquid chromatograph—mass spectrometer analytical sy...

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Bibliographic Details
Published in:Journal of Chromatography A 1974, Vol.99, p.13-21
Main Authors: Horning, E.C., Carroll, D.I., Dzidic, I., Haegele, K.D., Horning, M.G., Stillwell, R.N.
Format: Article
Language:English
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Summary:Atmospheric pressure ionization (API) mass spectrometry is a novel form of mass spectrometry in which ions are generated in a reaction chamber external to the low-pressure region of a quadrupole mass spectrometer. Using this ionization technique a liquid chromatograph—mass spectrometer analytical system was constructed. The entire effluent stream from the chromatograph is vaporized throught the API source. The primary ionization source for this work was a corona discharge The very high ion densities generated by the corona discharge extend the linear range of the API source into the microgram region.
ISSN:0021-9673
DOI:10.1016/S0021-9673(00)90841-0