Continuous-flow fast atom bombardment mass spectrometry

The continuous-flow fast atom bombardment probe performs equally well with or without a high-performance liquid chromatography column producing clean spectra containing little or no background noise. Its function as a liquid chromatography-mass spectrometry interface for labile and involatile sample...

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Bibliographic Details
Published in:Journal of Chromatography A 1987, Vol.394 (1), p.15-20
Main Authors: Ashcroft, Alison E., Chapman, John R., Cottrell, John S.
Format: Article
Language:English
Subjects:
Analytical chemistry
Chemistry
Chromatographic methods and physical methods associated with chromatography
Exact sciences and technology
Other chromatographic methods
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Summary:The continuous-flow fast atom bombardment probe performs equally well with or without a high-performance liquid chromatography column producing clean spectra containing little or no background noise. Its function as a liquid chromatography-mass spectrometry interface for labile and involatile samples has been illustrated with reference to dansylated amino acids. The versatility of the new probe has been exemplified by on-line enzymatic peptide sequencing.
ISSN:0021-9673
DOI:10.1016/S0021-9673(01)94156-1