Classifying eluents in reversed-phase thin-layer chromatography by spectral mapping

The retentions of 17 substituted symmetrical triazine derivatives were determined in reversed-phase thin-layer chromatography using 27 organic solvents miscible with water. The data matrix was evaluated by multivariate techniques. It was established that a higher solvent lipophilicity means a higher...

Full description

Saved in:
Bibliographic Details
Published in:Journal of Chromatography A 1984-01, Vol.286, p.131-137
Main Authors: CSERHATI, T, BORDAS, B
Format: Article
Language:English
Subjects:
Analytical chemistry
Chemistry
Chromatographic methods and physical methods associated with chromatography
Exact sciences and technology
Gas chromatographic methods
Other chromatographic methods
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The retentions of 17 substituted symmetrical triazine derivatives were determined in reversed-phase thin-layer chromatography using 27 organic solvents miscible with water. The data matrix was evaluated by multivariate techniques. It was established that a higher solvent lipophilicity means a higher solvent strength, but the lipophilicity explains only about 67% of total variance. The influence of lipophilicity was the lowest with acetonitrile, tetrahydrofuran, methyl ethyl ketone, di-methylformamide and ethylene glycol. Ch 3 and CH 2 groups increased significantly and primary OH, COC and ▪ groups decreased the solvent strength. The presence and position of nitrogen and oxygen atoms and free hydroxyl groups govern the solvent selectivity in reversed-phase thin-layer chromatography.
ISSN:0021-9673
DOI:10.1016/S0021-9673(01)99180-0