Optimisation of a programmed split–splitless injector in the gas chromatographic–mass spectrometric determination of organochlorine pesticides

Large-volume injection techniques in gas chromatography are used to compensate for the at times limited detection sensitivity of mass spectrometric detection. In this work a programmed split–splitless injector in solvent split mode was employed to determine organochlorine pesticides in environmental...

Full description

Saved in:
Bibliographic Details
Published in:Journal of Chromatography A 2002-06, Vol.958 (1), p.17-24
Main Authors: Concha-Graña, E., Turnes-Carou, M.I., Muniategui-Lorenzo, S., López-Mahı́a, P., Fernández-Fernández, E., Prada-Rodrı́guez, D.
Format: Article
Language:English
Subjects:
Analysis methods
Analytical chemistry
Applied sciences
Chemistry
Chromatographic methods and physical methods associated with chromatography
Exact sciences and technology
Gas chromatographic methods
Gas Chromatography-Mass Spectrometry - methods
Hydrocarbons, Chlorinated
Insecticides - analysis
Pesticides
Pollution
Sensitivity and Specificity
Soil and sediments pollution
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Large-volume injection techniques in gas chromatography are used to compensate for the at times limited detection sensitivity of mass spectrometric detection. In this work a programmed split–splitless injector in solvent split mode was employed to determine organochlorine pesticides in environmental samples. The injection conditions were selected by a Plackett-Burman design followed by a central composite design. The LODs obtained in the optimum conditions were compared with those obtained with splitless-MS and splitless-ECD. Finally, the method was applied to a soil sample.
ISSN:0021-9673
DOI:10.1016/S0021-9673(02)00324-2