Sensitive method for the determination of 3-chloropropane-1,2-diol and 2-chloropropane-1,3-diol by capillary gas chromatography with mass spectrometric detection

An improved routine method for the determination of 3-chloropropane-1,2-diol (3-MCPD) and 2-chloropropane-1,3-diol (2-MCPD) in different savoury foods using capillary gas chromatography with mass spectrometric detection is presented. Monochloropropanediols were extracted from Extrelut columns with d...

Full description

Saved in:
Bibliographic Details
Published in:Journal of Chromatography A 1998-04, Vol.802 (2), p.325-333
Main Authors: Meierhans, D.C, Bruehlmann, S, Meili, J, Taeschler, C
Format: Article
Language:English
Subjects:
Biological and medical sciences
Chloropropanediols
Food industries
Fundamental and applied biological sciences. Psychology
General aspects
Miscellaneous
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:An improved routine method for the determination of 3-chloropropane-1,2-diol (3-MCPD) and 2-chloropropane-1,3-diol (2-MCPD) in different savoury foods using capillary gas chromatography with mass spectrometric detection is presented. Monochloropropanediols were extracted from Extrelut columns with diethyl ether and derivatised with acetone to the corresponding dioxolanes. Detection was performed on two different mass spectrometers using single ion monitoring, to reach ultimate sensitivity in the low μg/kg range. A limit of detection of 1 μg kg −1 was achieved using Extrelut 20 for extraction. The method proved to be fast and reliable and showed good recoveries and good accuracy, confirmed by successful participation in two ring test studies. Results of analyses of finished goods, such as seasonings and soy sauces, often containing MCPDs only in the sub-ppb level, are presented.
ISSN:0021-9673
DOI:10.1016/S0021-9673(97)01188-6