Germination inhibitory constituents from Erigeron annuus

• Published in: Phytochemistry (Oxford) 2002-09, Vol.61 (2), p.175-179
• Main Authors: Oh, Hyuncheol, Lee, Sunyoung, Lee, Ho-Sub, Lee, Dong-Heon, Lee, Seung Yeob, Chung, Hun-Taeg, Kim, Tae Soo, Kwon, Tae-Oh
• Format: Article
• Language: English
• Subjects: (5-Butyl-3-oxo-2,3-dihydro-furan-2-yl)-acetic acid; Agronomy. Soil science and plant productions; Asteraceae - chemistry; Biological and medical sciences; Compositae; Economic plant physiology; Erigeron annuus; Flowers - chemistry; Fundamental and applied biological sciences. Psychology; Germination - drug effects; Germination inhibitors; Growth and development; Growth regulators; Inhibitory Concentration 50; Lactuca - drug effects; Magnetic Resonance Spectroscopy; Mass Spectrometry; Metabolism; Molecular Structure; Plant Extracts - pharmacology; Plant physiology and development; Seeds - drug effects
• ISSN: 0031-9422; 1873-3700
• DOI: 10.1016/S0031-9422(02)00236-4

(5-Butyl-3-oxo-2,3-dihydrofuran-2-yl)-acetic acid has been isolated from the flowers of Erigeron annuus as one of four germination inhibitory constituents. (5-Butyl-3-oxo-2,3-dihydrofuran-2-yl)-acetic acid was isolated from the flowers of Erigeron annuus as one of four germination inhibitory constituents. Its structure was determined by analysis of MS and NMR spectroscopic data. Three known compounds, 3-hydroxy-pyran-4-one, 4-hydroxycinnamic acid, and 3,4-dihydroxycinnamic acid methyl ester were also identified as active constituents. These compounds showed 50% inhibitory effects (IC 50) on the germination of lettuce seed at concentrations of 2.13±0.03, 12.85±0.56, 4.97±0.24, and 4.87±0.25 mM, respectively. 4-Hydroxybenzoic acid was used as a positive control, displaying an IC 50 value of 4.02±0.39 mM.