Bioactive phenolic glycosides from Amburana cearensis

Coumarin ( 1) and two new phenolic glycosides have been isolated from the stem bark of Amburana cearensis, a tree reported in the Chacobo pharmacopoeia to be used against fever-causing diseases. The novel compounds were identified as: 4-(O-β- d-glucopyranosyl)-hydroxy-7-(3′,4′-dihydroxy-benzoyl)-ben...

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Bibliographic Details
Published in:Phytochemistry (Oxford) 1999-01, Vol.50 (1), p.71-74
Main Authors: Bravo B, José A, Sauvain, Michel, Gimenez T, Alberto, Muñoz O, Victoria, Callapa, Jorgia, Le Men-Olivier, Louisette, Massiot, Georges, Lavaud, Catherine
Format: Article
Language:English
Subjects:
Amburana cearensis
Biological activities
Biological and medical sciences
Chemical constitution
Coumarin
Fundamental and applied biological sciences. Psychology
General pharmacology
Leguminosae
Medical sciences
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
Phenolic glycosides
Plant physiology and development
Stem-bark
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Summary:Coumarin ( 1) and two new phenolic glycosides have been isolated from the stem bark of Amburana cearensis, a tree reported in the Chacobo pharmacopoeia to be used against fever-causing diseases. The novel compounds were identified as: 4-(O-β- d-glucopyranosyl)-hydroxy-7-(3′,4′-dihydroxy-benzoyl)-benzyl alcohol ( 2) and 4-(O-β- d-glucopyranosyl)-hydroxy-7-(3′-methoxy-,4′-hydroxy-benzoyl)-benzyl alcohol ( 3). All three compounds were assayed in vitro for antimalarial, antiprotozoal, antifungal and antibacterial activities.
ISSN:0031-9422
1873-3700
DOI:10.1016/S0031-9422(98)00497-X