Determination of significant parameters for improved griseofulvin production in a batch bioreactor by Taguchi's method

Taguchi's method was applied to evaluate the significant parameters for griseofulvin production by Penicillium griseofulvum MTCC 1898 in a batch bioreactor. Physical parameter, viz., controlled pH, agitation and aeration had a significant influence on griseofulvin production when compared with...

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Bibliographic Details
Published in:Process biochemistry (1991) 2003-01, Vol.38 (6), p.877-880
Main Authors: Venkata Dasu, V, Panda, T, Chidambaram, M
Format: Article
Language:English
Subjects:
Batch culture
Griseofulvin
Penicillium griseofulvum
Taguchi's method
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Summary:Taguchi's method was applied to evaluate the significant parameters for griseofulvin production by Penicillium griseofulvum MTCC 1898 in a batch bioreactor. Physical parameter, viz., controlled pH, agitation and aeration had a significant influence on griseofulvin production when compared with chemical parameters and were considered as significant ones.
ISSN:1359-5113
1873-3298
DOI:10.1016/S0032-9592(02)00068-7