The mono-functionalization of symmetrical polyamines

Procedures developed to effectively desymmetrize symmetrical diamines and polyamines are reviewed.

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Bibliographic Details
Published in:Tetrahedron 2002-04, Vol.58 (16), p.3111-3128
Main Authors: Bender, John A., Meanwell, Nicholas A., Wang, Tao
Format: Article
Language:English
Subjects:
acylation
alkylation
arylation
aza macrocycles
cyclam
cyclen
desymmetrization
diamines
piperazines
regiocontrol
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Description
Summary:Procedures developed to effectively desymmetrize symmetrical diamines and polyamines are reviewed.
ISSN:0040-4020
1464-5416
DOI:10.1016/S0040-4020(02)00165-5